Artesunate/amodiaquine - Wikipedia
网页Artesunate/amodiaquine, sold under the trade name Camoquin among others, is a medication used for the treatment of malaria. [3][4] It is a fixed-dose combination of artesunate and amodiaquine. [3] Specifically it recommended for acute uncomplicated Plasmodium falciparum malaria. [5] It is taken by mouth.
ARTESUNATE/AMODIAQUINE = AS/AQ oral | MSF Medical …
网页Indications. Treatment of uncomplicated falciparum malaria. Treatment of uncomplicated malaria due to other Plasmodium species, when chloroquine cannot be used. Completion treatment following parenteral therapy for severe malaria. Forms and strengths.
Dosing accuracy of artesunate and amodiaquine as treatment …
网页AS was dosed correctly in >99% with all regimens. Loose AQ by weight was 98% correct. The co-blister AQ overdosed 18% of patients when dosed by age and underdosed 13% by weight. Low weight was an independent risk factor for overdosing.
The efficacy and safety of a new fixed-dose combination of …
网页2009年3月16日 · Artesunate (AS) plus amodiaquine (AQ) is one artemisinin-based combination (ACT) recommended by the WHO for treating Plasmodium falciparum malaria. Fixed-dose AS/AQ is new, but its safety and efficacy are hitherto untested. Methods.
The effect of dosing strategies on the therapeutic efficacy of ...
网页2015年3月31日 · Artesunate-amodiaquine (AS-AQ) is one of the most widely used artemisinin-based combination therapies (ACTs) to treat uncomplicated Plasmodium falciparum malaria in Africa. We investigated the impact of different dosing strategies on the efficacy of this combination for the treatment of falciparum malaria.
The initial pharmaceutical development of an …
网页2011年5月23日 · This paper reports on the initial phases of the pharmaceutical development of an artesunate-amodiaquine (ASAQ) bilayer co-formulation tablet, undertaken following pre-formulation studies by a network of scientists and industrials from institutions of both industrialized and low income countries. Methods.
Safety and efficacy of artesunate-amodiaquine combined with …
网页2019年10月10日 · Children (6–59 months) with uncomplicated falciparum malaria in Burkina Faso were treated with artesunate-amodiaquine (AS-AQ) and randomized to MB (15 mg/kg/day for 3 days) or PQ (0.25 mg/kg at day 2) with the aim to show non-inferiority of the MB regimen with regard to haematological recovery at day 7 (primary endpoint).
Efficacy of artesunate-amodiaquine for treating uncomplicated ...
网页2009年8月23日 · Artesunate and amodiaquine (AS&AQ) is at present the world's second most widely used artemisinin-based combination therapy (ACT). It was necessary to evaluate the efficacy of ACT, recently adopted by the World Health Organization (WHO) and deployed over 80 countries, in order …
Fixed artesunate–amodiaquine combined pre-formulation study …
网页2010年8月16日 · Artemisinin-based combination therapies, including artesunate (AS) + amodiaquine (AQ), are the currently recommended first-line treatment of uncomplicated falciparum malaria. Fixed-dose co-formulations offer logistic and adherence advantages. This paper reports the initial research phase of the …
Evaluating artesunate-amodiaquine deployment, efficacy and …
网页2019年3月14日 · The clinical efficacy of AS-AQ is very high but its effectiveness in the field varies considerably. This study aimed at comparing the efficacy, effectiveness and safety of AS-AQ fixed dose combination (FDC) and non-fixed formulation (non-FDC) in controlled and real-life settings using a pharmacological model of antimalarial treatment.