Apoptosis - Wikipedia
网页Apoptosis (from Ancient Greek: ἀπόπτωσις, romanized: apóptōsis, lit. 'falling off') is a form of programmed cell death that occurs in multicellular organisms and in some eukaryotic, single-celled microorganisms such as yeast. [1] Biochemical events lead to characteristic cell changes (morphology) and death. [2]
Apoptosis - StatPearls - NCBI Bookshelf
网页2024年4月30日 · Many years later, apoptosis is defined as the ATP-dependent, enzyme-mediated, genetically programmed death of cells that are either no longer required or pose a threat to the organism. Apoptosis results when the cytoskeleton (by proteases) and DNA (by endonucleases) break down through several pathways that are homeostatic or pathological.
Apoptosis – Definition and Importance - Science Notes and Projects
网页2024年3月20日 · Apoptosis comes from the Greek words “apo” (away from) and “ptosis” (falling), literally meaning the “falling off” of cells. It is a form of programmed cell death, where cells dismantle themselves in a controlled and regulated manner. This mechanism is crucial for maintaining cellular integrity and organismal homeostasis.
Apoptosis | Cell Death, Cytology & Signaling Pathways
网页2024年9月7日 · apoptosis, in biology, a mechanism that allows cells to self-destruct when stimulated by the appropriate trigger. Apoptosis can be triggered by mild cellular injury and by various factors internal or external to the cell; the damaged cells are then disposed of in an orderly fashion.
Apoptotic cell death in disease—Current understanding of the
网页2023年4月26日 · Apoptosis is a form of regulated cell death (RCD) that involves proteases of the caspase family.
50 years on and still very much alive: ‘Apoptosis: a basic ... - Nature
网页2022年11月11日 · Apoptotic cells display distinct morphological features, including separation from other cells, nuclear condensation, membrane blebbing, fragmentation and cell shrinkage, and the...
Programmed Cell Death (Apoptosis) - Molecular Biology of the …
网页Apoptosis Is Mediated by an Intracellular Proteolytic Cascade. Cells that die as a result of acute injury typically swell and burst. They spill their contents all over their neighbors—a process called cell necrosis —causing a potentially damaging inflammatory response.
The biochemical pathways of apoptotic, necroptotic, pyroptotic, …
网页2024年1月4日 · Apoptosis is the first identified form of regulated cell death and is carried out by intracellular caspase-3 and caspase-7, which cleave diverse intracellular substrates, causing cell shrinkage, chromatin fragmentation, membrane blebbing, and breakdown into membrane-wrapped vesicles called apoptotic bodies.
Necroptosis, pyroptosis and apoptosis: an intricate game of cell …
网页2021年3月30日 · Apoptosis is a mechanism of regulated cell death conserved across the animal kingdom that has been the subject of intensive research for the past three decades and was, for most of this...
Apoptosis and apoptotic body: disease message and therapeutic …
网页2019年1月1日 · Apoptosis is a highly regulated process of cell death. Unlike necrosis which is a traumatic version of cell death, apoptosis is a rational and active decision made to sacrifice specific cells for the greater benefits of the organism. It is a normal physiologic process routinely carried out in multicellular organisms [1].