Brodifacoum - Wikipedia
网页Brodifacoum is a highly lethal 4-hydroxycoumarin vitamin K antagonist anticoagulant poison. In recent years, it has become one of the world's most widely used pesticides . It is typically used as a rodenticide , but is also used to control larger pests such as possums .
Rodenticide Poisoning: What to Do After Exposure
网页Second-generation anticoagulants (dipha-cinone, difethialone, chlorophacinone, brodifacoum): 4 weeks; Cautions: To avoid an anaphylactic reaction, vitamin K 1 should not be administered IV; anaphylactic reactions may also occur when it is administered IM or SC.
网页Brodifacoum is a very effective toxin for rodents because it is highly toxic (a lethal dosage can be consumed in one feeding) and slow acting (symptoms do not appear for a couple of days after feeding). The delayed onset of symptoms avoids animals becoming bait shy by associating feeling sick with eating the bait.
Superwarfarin (Long-Acting Anticoagulant Rodenticides) Poisoning…
网页The two most commonly encountered superwarfarins in clinical poisoning are bromadiolone and brodifacoum. 45, 46 Both bromadiolone and brodifacoum are warfarin/4-hydroxycoumarin derivatives. 38 In the broad sense of the term used clinically, superwarfarins also encompass long-acting anticoagulant rodenticides which are not …
Vitamin K1 Treatment Duration in Patients with Brodifacoum Poisoning ...
网页2020年4月29日 — Brodifacoum, a long-acting vitamin K epoxide cycle antagonist, is a rodenticide encountered in intentional ingestions and as a contaminant of some synthetic cannabinoid products. 1 Serious...
‘It’s really scary’: How rat poisons are wreaking havoc on ... - AAAS
网页2024年7月10日 — Brodifacoum has been found in blue cod, limpets, and mussels. In Australia, a study this year identified brodifacoum and other rodenticides in dead frogs. Some animals likely ingest the poisons when they eat contaminated prey, but contaminated soil and even contaminated rodent feces could also pose a threat, researchers say.
Brodifacoum poisoning: A clear and present danger to public …
网页2017年2月15日 — Amongst the superwarfarins typically incorporated into rodent bait, brodifacoum (BDF) is the most widely used. Poisoning by ingestion, inhalation or absorption through the skin of BDF shows no signs or symptoms in humans other than delayed (after several days) development of severe, long-lasting (up to months) bleeding …
The Long-Lasting Rodenticide Brodifacoum Induces …
网页2017年6月27日 — We now characterized the neurological effects of brodifacoum (BDF), one of the most widely used superwarfarins, in adult male Sprague Dawley rats. Dosing curves established the acute oral lethal dose for BDF as 221 ± 14 μg/kg.
The relative toxicity of brodifacoum enantiomers - PMC
网页2019年5月5日 — Brodifacoum (BDF) is a potent, long-acting anticoagulant rodenticide that can cause fatal poisoning in humans. The chemical structure of BDF includes 2 chiral carbons, resulting in 2 pairs of diastereomers, BDF …
Efficacy of rodenticide baits with decreased concentrations of ...
网页2019年11月14日 — Buckle, A. P., Klemann, N. & Prescott, C. V. Brodifacoum is effective against Norway rats (Rattus norvegicus) in a tyrosine139cysteine focus of anticoagulant resistance in Westphalia, Germany.