Granisetron - Wikipedia
网页Granisetron is a serotonin 5-HT 3 receptor antagonist used as an antiemetic to treat nausea and vomiting following chemotherapy and radiotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata.
Granisetron Uses, Side Effects & Warnings - Drugs.com
网页2023年9月18日 · Granisetron blocks the actions of chemicals in the body that can trigger nausea and vomiting. Granisetron is used to prevent nausea and vomiting that may be caused by medicine to treat cancer (chemotherapy or radiation). Granisetron may also be used for purposes not listed in this medication guide.
granisetron - UpToDate
网页…First-generation serotonin antagonists – The first-generation serotonin antagonists (ie, ondansetron, granisetron, dolasetron, and, outside the United States, tropisetron) are equally efficacious for PONV at equipotent …
DailyMed - GRANISETRON HYDROCHLORIDE tablet
网页2024年2月29日 · Granisetron hydrochloride tablets USP are indicated for the prevention of: Nausea and vomiting associated with initial and repeat courses of emetogenic cancer therapy, including high-dose ... CONTRAINDICATIONS. Granisetron hydrochloride tablets are contraindicated in patients with known hypersensitivity to the drug or any of its …
Granisetron: MedlinePlus Drug Information
网页Granisetron is used to prevent nausea and vomiting caused by cancer chemotherapy and radiation therapy. Granisetron is in a class of medications called 5-HT 3 receptor antagonists. It works by blocking serotonin, a natural substance in the body that causes nausea and vomiting.
Granisetron - NCI - National Cancer Institute
网页Granisetron is approved to be used alone or with other drugs to prevent: Nausea and vomiting caused by chemotherapy. It is used in adults. Granisetron is also available in a different form called granisetron hydrochloride. For more information, see the Drug Information Summary for Granisetron Hydrochloride.
Granisetron | Drugs | BNF | NICE
网页Granisetron is a specific 5HT 3 -receptor antagonist which blocks 5HT 3 receptors in the gastro-intestinal tract and in the CNS. Indications and dose. Nausea and vomiting induced by cytotoxic chemotherapy for planned duration of 3–5 days where oral antiemetics cannot be used. By transdermal application using patches. Adult.
GRANISETRON- granisetron hydrochloride injection, solution - DailyMed
网页2022年11月15日 · Granisetron Hydrochloride Injection, USP is a serotonin-3 (5-HT 3) receptor antagonist indicated for: The prevention of nausea and/or vomiting associated with initial and repeat courses of emetogenic cancer therapy, including high-dose cisplatin. The prevention and treatment of postoperative nausea and vomiting in adults.
Granisetron Monograph for Professionals - Drugs.com
网页2023年11月27日 · Granisetron (Monograph) Brand name: Kytril. Drug class: 5-HT3 Receptor Antagonists. Chemical name: endo-1-Methyl-N- (9-methyl-9-azabicyclo [3.3.1]non-3-yl)-1H-indazole-3-carboxamide monohydrochloride. Molecular formula: …
Newest Drugs for Chronic Unexplained Nausea and Vomiting
网页One of the older 5-HT 3 antagonists, granisetron, has been reformulated for other methods of administration to optimize delivery to patients who may have difficulties absorbing the drug due to persistent vomiting.
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