Isothermal microcalorimetry - Wikipedia
网页Isothermal microcalorimetry (IMC) is a laboratory method for real-time, continuous measurement of the heat flow rate (μJ/s = μW) and cumulative amount of heat (J) consumed or produced at essentially constant temperature by a specimen placed in an IMC instrument.
Microcalorimetry - an overview | ScienceDirect Topics
网页Microcalorimetry is an ultrasensitive development of the technique that measures very small heat changes in small sample volumes, making it suitable for biomaterials. Applications range from confirming intended binding targets in small molecule drug discovery to the development of stable biotherapeutics.
Microcalorimetry | Interactions & Stability of Biomolecules
网页Microcalorimetry is used to study reactions involving biomolecules, including interactions between molecules and conformational changes such as protein folding. Applications range from confirming intended binding targets in small molecule drug discovery to the development of stable biotherapeutics.
Microcalorimetry: a response to challenges in modern biotechnology
网页2007年12月10日 · Over the last three decades microcalorimetry has established its place as a key technique in the fundamental research on biomolecules. More recently, however, the use of microcalorimetry has become more applied and problem‐driven.
Microcalorimetry - an overview | ScienceDirect Topics
网页Microcalorimetry involves the measurement of small amounts of heat that microorganisms produce during growth. The heat production is closely related to cellular catabolic activities and can be measured by very sensitive calorimeters such as the Calvet instrument. This instrument can detect 0.01 calories of heat per hour from a 10−1 sample.
Enabling direct microcalorimetric measurement of metabolic …
网页2023年5月9日 · Here we present a new, versatile, and robust microcalorimetric differential design based on the integration of heat flux sensors on top of microfluidic channels.
High Precision Microcalorimetry: Apparatus, Procedures, and …
网页Microcalorimetry is an important technique for the measurement of heats of reaction in solution. Since small amounts of solution (typically less than one mL) are required, the technique finds many applications in the study of biochemical and biological systems [ …
1.3.6: Calorimetry - Titration Microcalorimetry
网页2024年5月20日 · 1.3.6: Calorimetry - Titration Microcalorimetry. In a common type of calorimeter, aliquots of one liquid (solution or solvent) are injected into a sample cell containing another liquid. The rise in temperature accompanying injection of each aliquot is recorded. The calorimeter is calibrated electrically.
网页Microcalorimetry was developed to measure the meta-bolic heat output of small samples of cells and chemical reactions. It has been applied in the elds of micro-fi biology13–15, soil science16 ...
Microcalorimetric assays for measuring cell growth and …
网页2015年4月1日 · To monitor the metabolic activity of cells or microbial cultures, researchers often use so-called metabolic assays based on the reduction of tetrazolium dyes or resazurin by dehydrogenase mostly from the respiratory chain [21].
跳至内容