Monooxygenase - Wikipedia
网页Monooxygenases are enzymes that incorporate one hydroxyl group (−OH) into substrates in many metabolic pathways.
单加氧酶 - 维基百科，自由的百科全书
网页单加氧酶 （英語： Monooxygenase）又称 單氧化酶 、 混合功能氧化酶 （mixed functional oxidase），在多种代谢途径中催化一分子氧（O 2）中的一个氧原子与 底物 结合，形成一个 羟基 （发生 羟化）的产物；另一个氧原子被还原形成一分子水，并同时伴随着 NADH 或 NADPH 的氧化 [2][3]。 参考文献. ^ PDB 2Y6Q; Volkers G, Palm GJ, Weiss MS, Wright GD, Hinrichs W. Structural basis for a new tetracycline resistance mechanism relying on the …
Monooxygenases as biocatalysts: Classification, mechanistic …
网页Monooxygenases are enzymes that catalyze the insertion of a single oxygen atom from O (2) into an organic substrate. In order to carry out this type of reaction, these enzymes need to activate molecular oxygen to overcome its …
Properties and Mechanisms of Flavin-Dependent …
网页2022年2月27日 · Flavin adenine dinucleotide (FAD)-dependent monooxygenases (FMOs) catalyze many oxidation reactions with chemo-, regio-, and stereo-selectivity, and they are involved in the synthesis of many natural products. In this review, we introduce the mechanisms for different FMOs, with the classical FAD …
Flavin-containing monooxygenases: new structures from old …
网页2019年12月23日 · 2 Altmetric. Metrics. A study reports the structures of membrane-bound flavin-containing monooxygenases (FMOs), solved using reconstructed ancestral mammalian FMOs. The models provide a structural...
Monooxygenase, peroxidase and peroxygenase properties and …
网页This review examines the monooxygenase, peroxidase and peroxygenase properties and reaction mechanisms of cytochrome P450 (CYP) enzymes in bacterial, archaeal and mammalian systems. CYP enzymes catalyze monooxygenation reactions by inserting one oxygen atom from O2 into an enormous number and variet …
Monooxygenases as biocatalysts: Classification, mechanistic …
网页2010年3月1日 · Monooxygenases are enzymes that catalyze the insertion of a single oxygen atom from O 2 into an organic substrate. In order to carry out this type of reaction, these enzymes need to activate molecular oxygen to overcome its spin-forbidden reaction with the organic substrate.
Structural insight into the electron transfer pathway of a self ...
网页2020年5月29日 · Cytochrome P450 monooxygenases are a group of heme-thiolate proteins that catalyze reactions related to natural products biosynthesis, carbon source assimilation, cellular...
Monooxygenase - an overview | ScienceDirect Topics
网页Monooxygenases are defined as a group of enzymes that catalyze the incorporation of one atom of molecular oxygen into a substrate, with the other being reduced to water. Therefore, these enzymes are some times referred to as mixed function oxidases or mixed function oxygenases.
Baeyer–Villiger Monooxygenases: Tunable Oxidative Biocatalysts
网页2019年10月25日 · This monooxygenase catalyzes the Baeyer–Villiger oxidation of one of the four rings of premithramycin B, forming the lactone, which is later converted to mithramycin DK. As other BVMOs, MtmoIV uses NADPH and FAD as hydride donor and prosthetic group, respectively.
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