Allotransplantation - Latest research and news | Nature
网页2024年7月31日 · Allotransplantation is the transplantation of an organ or tissue from one individual to another of the same species with a different genotype. The transplant is called an allograft. This is ...
Allotransplantation - Wikipedia
网页Allotransplant (allo- meaning "other" in Greek) is the transplantation of cells, tissues, or organs to a recipient from a genetically non-identical donor of the same species. [1] The transplant is called an allograft, allogeneic transplant, or homograft. Most human tissue and organ transplants are allografts.
Composite tissue allotransplantation: opportunities and challenges
网页2019年3月6日 · Vascularized composite allotransplants (VCAs) have unique properties because of diverse tissue components transplanted en mass as a single unit. In addition to surgery, this type of transplant also faces enormous immunological challenges that demand a detailed analysis of all aspects of alloimmune …
Composite tissue allotransplantation: opportunities and …
网页2019年3月6日 · Vascularized composite allotransplants (VCAs) are grafts that are composed of multiple different tissues but are transplanted together as a single unit. A typical...
Classic and Current Opinions in Human Organ and Tissue …
网页2022年11月1日 · Ensuring allograft tolerance has become an ideal treatment goal in clinical transplant practice. Mitigating immunological reactions in allotransplantation and suppressing infections and tumor formation are significant hurdles in transplant practice.
Allotransplantation - an overview | ScienceDirect Topics
网页Allotransplantation is the gold standard treatment for end-stage organ failure. However, this life-saving treatment is limited by the challenge of controlling the immune system to prevent damage to the foreign organ.
Cellular Therapies in Solid Organ Allotransplantation: Promise …
网页Cellular therapies in transplantation can be broadly categorized into five groups: donor specific transfusions (DSTs), hematopoietic stem cell transplant (HSCT), mesenchymal stem cell based therapy (MSC), manufactured immune cell therapy (using various regulatory cells), and modified immune cell (MIC) therapy.
The Future of Transplantation | New England Journal of Medicine
网页2022年6月22日 · Clinical organ xenotransplantation invariably failed, whereas clinical organ allotransplantation rose to become a primary treatment for failure of the heart, kidneys, liver, and lungs. Still, a...
The innate immune response to allotransplants: mechanisms and …
网页2019年2月25日 · Transplantation-associated ischemia reperfusion injury (IRI) causes inflammatory cell death (e.g., ferroptosis) in host and donor cells, leading to the release of damage-associated...
Allotransplantation - an overview | ScienceDirect Topics
网页2013年8月15日 · Allotransplantation is the most common treatment for end stage kidney, liver, lung, and heart disease. In order to accommodate the allograft, the recipient must be immune-suppressed, to prevent rejection of the graft by the innate and adaptive immune system.
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