Dopexamine - Wikipedia
网页Mechanism of action. Dopexamine stimulates beta-2 adrenergic receptors and peripheral dopamine receptor D1 and dopamine receptor D2. It also inhibits of neuronal re-uptake of norepinephrine (Uptake-1).
Dopexamine - an overview | ScienceDirect Topics
网页Dopexamine is a synthetic catecholamine which has marked activity at β2 -receptors with a lesser action at β 1 and dopaminergic sites. It improves CO through a positive inotropic effect, while causing vasodilation, reducing afterload and improving renal perfusion.
Dopexamine: Uses, Interactions, Mechanism of Action - DrugBank …
网页Drug created at October 20, 2016 21:55 / Updated at August 27, 2024 19:15. Dopexamine has been used in trials studying the diagnostic and treatment of Free Flap, Oral Cancer, Hypotension, Septic Shock, and Head and Neck Cancer.
Dopexamine - an overview | ScienceDirect Topics
网页Dopexamine is a synthetic dopamine analogue that acts on dopaminergic and β 2-receptors to cause smooth muscle relaxation in the renal and mesenteric arterial beds. Although it has no direct β 1 - or α-adrenoceptor activity, dopexamine does
Dopexamine | C22H32N2O2 | CID 55483 - PubChem
网页Dopexamine | C22H32N2O2 | CID 55483 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Dopexamine: immunomodulatory, hemodynamic, or both?
网页2013年5月13日 · Dopexamine is a dopamine analog that stimulates β-adrenergic and dopamine 1 and 2 receptors, conferring some vasodilatory effects. Dopexamine has classically been considered a vasoactive agent with inotropic effects, perhaps with more prominent effects in some regional vascular beds.
Dopexamine can attenuate the inflammatory response and …
网页2013年3月28日 · Dopexamine is a dopamine analogue with agonist activity at β2 and dopaminergic receptors. This spectrum of activity confers vasodilator actions in addition to chronotropic and mild inotropic effects.
Dopexamine: a novel agonist at peripheral dopamine receptors …
网页2016年10月7日 · The combination of agonist properties at peripheral dopamine receptors and at beta 2-adrenoceptors, with little or no activity at alpha- and beta 1-adrenoceptors gives dopexamine a novel pharmacological profile. This may confer advantages over dopamine in the treatment of acute heart failure.
Dopexamine (Dopacard, Speywood) - ScienceDirect
网页1996年8月1日 · Dopexamine is used to provide haemody- namic support for patients with low cardiac output who are at risk of major organ failure as a result. It is currently licensed for short-term treatment of heart failure associated with car- diac surgery.
Dopexamine in congestive heart failure: how do the ... - Springer
网页Dopexamine is a newly developed sympathetic catecholamine which combines dopaminergic (DA-1) and β 2-adrenergic agonist activity with only minor β 1-adrenergic action. Thereby, this compound exerts systemic and preferential renal vasodilation, causing afterload reduction, increases in cardiac output, and improved renal perfusion in animals ...
跳至内容