Mimotope - Wikipedia
网页Mimotopes are a kind of peptide aptamers. When the term mimotope was first coined by Mario Geysen in 1986, [1] it was used to describe peptides mimicking epitopes. However, this concept has been extended to refer peptide mimic of all types of binding sites.
Mimotope - an overview | ScienceDirect Topics
网页Mimotope (MP) is a peptide with specific amino acid sequence that mimics the epitope of an antigen and binds to the corresponding antibody. SMCs are classified as haptens in immunochemistry and their epitopes could be simulated by MPs.
Mimotope - an overview | ScienceDirect Topics
网页Mimotope. In subject area: Immunology and Microbiology. Mimotopes are peptide sequences that are capable of inducing immune responses by mimicking the structural features of a non-linear protein epitope or of a non-protein (e.g. carbohydrate) epitope structure. From: Trends in Microbiology, 2006.
Mimotope-based allergen-specific immunotherapy: ready for …
网页2019年8月20日 · By mimicking the structural or physiochemical characteristics of epitopes, mimotopes are able to inhibit the binding of antibodies to the native antigen or to induce an epitope-specific antibody...
MimoDB 2.0: a mimotope database and beyond - PMC
网页2011年11月2日 · Mimotopes are peptides with affinities to given targets. They are readily obtained through biopanning against combinatorial peptide libraries constructed by phage display and other display technologies such as mRNA display, ribosome display, bacterial display and yeast display.
Computational identification of antibody-binding epitopes from mimotope …
网页2024年2月22日 · A mimotope is a peptide that mimics the structure of an epitope, and which, in its most strict definition, causes an antibody response that is similar to the one elicited by the epitope (Geysen et al., 1986). An antibody for a given antigen is expected to recognize mimotopes which mimic the corresponding epitope.
Mimotope vaccination – from allergy to cancer - PMC
网页2016年10月2日 · Mimotopes are peptides mimicking protein, carbohydrates or lipid epitopes and can be generated by phage display technology. When selected by antibodies, they represent exclusively B-cell epitopes and are devoid of antigen/allergen-specific T …
Mimotope vaccines: Epitope mimics induce anti-cancer antibodies
网页2007年10月10日 · Mimotopes are epitope-mimicking structures. When applied for immunizations they induce desired antibody specificities exclusively based on the principle of molecular mimicry. This is important as antibodies directed against tumor-associated antigens may harbor diverse biological effects depending on their epitope specificity.
MimoDB 2.0: a mimotope database and beyond - PubMed
网页Mimotopes are peptides with affinities to given targets. They are readily obtained through biopanning against combinatorial peptide libraries constructed by phage display and other display technologies such as mRNA display, ribosome display, bacterial display and yeast display. Mimotopes have been u ….
Mimotope discovery as a tool to design a vaccine against Zika …
网页2023年4月14日 · By definition, a mimotope is a peptide that emulates an epitope, and mimotopes related to the original antigen in sequence as well as mimotopes without apparent similarity have been reported. Both types of mimotopes have been able to elicit antibodies against the original epitope (Humbert et al., 2007 ; …
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