The SARS-CoV-2 nucleocapsid protein is dynamic, disordered
网页2021年3月29日 · The SARS-CoV-2 nucleocapsid (N) protein is an abundant RNA-binding protein critical for viral genome packaging, yet the molecular details that underlie this process are poorly understood. Here we...
The Nucleocapsid Protein of the SARS Coronavirus: Structure, …
网页By definition, nucleocapsid is a viral protein coat that surrounds the genome (either DNA or RNA). Nucleocapsid protein is the major constituent of a viral nucleocapsid. It is capable of associating with itself and with the genome, thus packaging the genome inside a …
The SARS-CoV-2 nucleocapsid protein: its role in the viral life cycle ...
网页2023年1月10日 · The SARS-CoV-2 nucleocapsid (N) protein plays an important role in the coronavirus life cycle, and participates in various vital activities after virus invasion. It has attracted a large amount of attention for vaccine and drug development.
Intracellular Ebola virus nucleocapsid assembly revealed by
网页6 天之前 · In-cell cryo-electron tomography has uncovered the Ebola virus nucleocapsid assembly and condensation processes. The resulting 9 Å map of fully assembled nucleocapsids within the viral replication factory further reveals that two different states of the nucleoprotein NP simultaneously co-exist: one as pairs polymerized along RNA to form the helical core and the other held RNA-free and ...
The SARS-CoV-2 Nucleocapsid Protein and Its Role in Viral …
网页2021年6月10日 · Like other coronaviruses, the nucleocapsid (N) protein is one of the most crucial structural components of SARS-CoV-2. This protein shares 90% homology with the severe acute respiratory syndrome coronavirus N protein, implying functional significance.
The SARS-CoV-2 nucleocapsid phosphoprotein forms mutually
网页2021年1月21日 · The multifunctional nucleocapsid (N) protein in SARS-CoV-2 binds the ~30 kb viral RNA genome to aid its packaging into the 80–90 nm membrane-enveloped virion. The N protein is composed of...
Structures of the SARS ‐CoV‐2 nucleocapsid and ... - The EMBO …
网页2020年9月11日 · Nucleocapsid (N) protein, which is the major structural component of the virion and is involved in viral replication, assembly and immune regulation, plays key roles in the viral life cycle.
Virus Nucleocapsid - an overview | ScienceDirect Topics
网页The nucleocapsid refers to the assembly of protein and nucleic acid (the genome) that remains after the viral envelope is removed. In the case of the negative-strand RNA viruses, the main structural protein of the nucleocapsid is an RNA-binding nucleoprotein (N) but it also contains several molecules of the viral RNA-dependent RNA polymerase.
The SARS-CoV-2 Nucleocapsid Protein and Its Role in Viral ... - PubMed
网页2021年6月10日 · Like other coronaviruses, the nucleocapsid (N) protein is one of the most crucial structural components of SARS-CoV-2. This protein shares 90% homology with the severe acute respiratory syndrome coronavirus N protein, implying functional significance.
Structural landscape of the respiratory syncytial virus nucleocapsids
网页2023年9月15日 · The resulting helical nucleocapsid (NC) shields the viral genetic material from recognition by the innate immune system while serving as template for replication and transcription by the...
跳至内容