Peimine, an Anti-Inflammatory Compound from Chinese Herbal …
网页2021年10月19日 · Peimine (Pm), an anti-inflammatory compound from Fritillaria, is known to inhibit some voltage-dependent ion channels and muscarinic receptors, but its interaction with ligand-gated ion channels remains unexplored. We have studied if Pm affects nicotinic acetylcholine receptors (nAChRs), since they play broad functional roles, both in the ...
Peimine (Verticine，贝母甲素) - 仅供科研 | 抗炎剂 | MCE
网页Peimine (Verticine; Dihydroisoimperialine) is an orally active natural product. Peimine has anti-inflammatory, analgesic and cough relieving effects. Peimine can be used in cancer and inflammation related research.
Peimine | C27H45NO3 | CID 131900 - PubChem
网页Peimine | C27H45NO3 | CID 131900 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, safety/hazards/toxicity information, supplier lists, and more.
Peimine, a main active ingredient of Fritillaria, exhibits anti ...
网页2016年6月1日 · Peimine is one of active ingredients of Fritillaria. Using the patch-clamp technique, we profiled the action of Peimine against selected ion channels stably expressed in HEK 293 cell lines. Our data indicated that Peimine was not only able to block the Nav1.7 ion channel but also preferably inhibited the Kv1.3 ion channel.
Peimine suppresses collagen-induced arthritis, activated fibroblast ...
网页Background and purpose: Peimine (PM), a main isosterol alkaloid component isolated from the bulbs of traditional Chinese herb Fritillaria cirrhosa D. Don, has been demonstrated to exhibit multiple pharmacological properties, including …
Peimine, an Anti-Inflammatory Compound from Chinese Herbal
网页2021年10月19日 · Peimine (Pm), an anti-inflammatory compound from Fritillaria, is known to inhibit some voltage-dependent ion channels and muscarinic receptors, but its interaction with ligand-gated ion channels remains unexplored. We have studied if Pm affects nicotinic acetylcholine receptors (nAChRs), since they play broad functional roles, both in the ...
Peimine inhibits variants of SARS‐CoV‐2 cell entry via blocking the ...
网页Peimine, also known as verticine, is a major pure compound in several species of Fritillaria. In addition, peimine has been demonstrated to play an important role in treating human diseases, including analgesic, antiasthmatic, antitussive, …
Frontiers | Transcriptomic and metabolic analyses reveal the …
网页2022年10月6日 · Peimine, peiminine, hupehenine, and peimisine are the main phytochemicals in Fritillaria plants (Che et al., 2020; Liu et al., 2021). In the present study, peimine, peiminine, and hupehenine were identified as positive DEMs, suggesting that the majority of the active components in F. hupehensis were higher in the I …
Identification of the Molecular Mechanisms of Peimine in the …
网页2020年3月2日 · Peimine (also known as verticine) is the major bioactive and characterized compound of Fritillariae Thunbergii Bulbus, a traditional Chinese medicine that is most frequently used to relieve a cough. Nevertheless, its molecular targets and mechanisms of action for cough are still not clear.
Peimine, a main active ingredient of Fritillaria, exhibits anti ...
网页Peimine is one of active ingredients of Fritillaria. Using the patch-clamp technique, we profiled the action of Peimine against selected ion channels stably expressed in HEK 293 cell lines. Our data indicated that Peimine was not only able to block the Nav1.7 ion channel but also preferably inhibited the Kv1.3 ion channel.