陈俊延说，抑制药物代谢的作用因人而异，可能长达数天或仅几个小时都有，吃完柚子相隔4小时也无法完全避免。对于肾功能不良的病人，服用慢性疾病用药更要考虑药物排除体外的速率，若是饮食突然改变，疾病控制可能会有变化。

Many of these drugs are metabolized by cytochrome P450 3A4 (CYP3A4), which has been estimated to be involved in the metabolism of ∼50% of prescription drugs and is therefore a common cause of ...

常用药物包括奈玛特韦利托那韦（Paxlovid）、阿兹夫定、莫诺拉韦、先诺特韦利托那韦、氢溴酸氘瑞米德韦、来瑞特韦、阿泰特韦利托那韦等，一般适用于轻、中症且伴有进展为重症高风险因素的成年患者，且应尽早用药，在症状首次出现的57天内使用为宜。

Aristada is a prescription drug used for schizophrenia. Find out about possible interactions with alcohol, other drugs, ...

John's wort. Irinotecan is, in part, eliminated by routes that are mediated by an isoform of P450, CYP3A4. The authors report that plasma levels of the active metabolite, SN-38, were decreased by ...

The drug is cleared by cytochrome P450 (CYP)3A4 metabolism. Peak plasma concentrations are achieved about 1.5 hours after oral administration. Its absorption is not affected by food. Eplerenone ...

One key enzyme is cytochrome P450 3A4, or CYP3A4. As the furanocoumarins in grapefruit are broken down in the body, their resulting derivatives can block the action of CYP3A4. Thus, instead of ...

Ratutrelvir was well-tolerated for 10 days and achieved consistent plasma levels in the predicted therapeutic window, without the need for ...

Research shows that St. John’s wort works as well as some antidepressants for the short-term treatment of depression. Be ...

Direct Oral Anticoagulants (DOACs) have significantly improved anticoagulation therapy – due to their ease of use, ...

Contraindicated With Strong Inhibitors of CYP450 3A4 Such as Ketoconazole or Itraconazole. Eplerenone is metabolized by the 3A4 isozyme of the CYP450 system; thus, when given with inhibitors of ...

Monday 9 March 2020 1 CYP = inf EUR inf inf CYP EUR rate for 09/03/2020 Sunday 8 March 2020 1 CYP = inf EUR inf inf CYP EUR rate for 08/03/2020 Saturday 7 March 2020 1 CYP = inf EUR inf inf CYP ...