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Conclusions These data identify HAMLET as a new, peroral agent for colon cancer prevention and treatment, especially needed in people carrying APC mutations, where colon cancer remains a leading cause ...

Objective Peroral endoscopic myotomy (POEM) has become standard treatment for achalasia with comparable efficacy to surgery. In most of published series, the length of myotomy is 12–13 cm. Shorter ...

1 The authors found that significantly more patients had treatment success after peroral endoscopic myotomy (POEM) than pneumatic dilation after 5 years of follow-up. Because their findings are ...

The POEM procedure is performed by endoscope. There is no incision in the chest or abdomen. The endoscope (a thin flexible tube) is passed through the patient's mouth into the esophagus. Using a blade ...

The purpose of this study is to decide the role this less invasive treatment (Peroral Endoscopic Myotomy) has in the treatment of patient's with achalasia. Participant eligibility includes age, gender ...

Feasibility studies of dermal delivery of paclitaxel with binary combinations of ethanol and isopropyl myristate: role of solubility, partitioning and lipid bilayer perturbation.

The accumulation of antibiotic resistance genes in pathogenic bacterial strains is an important cause of antibiotic treatment failure. Conjugative antibiotic resistance plasmids are key drivers of ...

Therapy also benefits from new technology such as the possibility of the peroral endoscopic myotomy. All these changes are not final and have been constantly revised. Good quality studies are still ...