Opioids were considered inappropriate for chronic pain management owing to concerns about adverse effects, tolerance, dependence and addiction. In the subsequent decades, several circumstances ...

In addition, some of the excipients used to prepare oral modified-release opioid products, particularly talc, may lead to serious complications if these products are parenterally abused.

What’s more, the mainstay therapy for severe acute and chronic pain — prescription opioids — has helped fuel an epidemic that kills tens of thousands of people each year. “We have to have ...

On 6 August, at the International Association for the Study of Pain (IASP) World Congress, an oral presentation held during a topical workshop on the use of opioid therapy for chronic pain ...

It's important to understand that patients with severe chronic pain often face higher mortality rates due to the underlying conditions — cancer, cardiovascular disease, respiratory problems, and even ...

Medication is the go-to treatment for pain, while severe chronic pain conditions are often treated with opioids, which bear many side effects and also raise concerns of addiction, misuse and even ...

A non-opioid drug for ... with moderate-to-severe osteoarthritis of the knee, raising the hope it could become a non-addictive option for patients needing chronic pain relief.

According to the guidelines, naloxone should be prescribed with every opioid prescription. The American Academy of Pediatrics (AAP) has published its first clinical practice guideline on the use ...

Decreasing adverse events from concurrent Vinca-alkaloid and azole antifungals in a pediatric oncology population: Patient safety improvement process. This is an ASCO Meeting Abstract from the 2024 ...

Vertex Pharma could be close to succeeding in the long-standing quest to find an alternative to potentially addictive opioids for ... treating moderate to severe acute pain in a pair of phase ...

A pilot study showed that a small amount of ketamine can reduce or eliminate the withdrawal symptoms associated with quitting fentanyl.