蛋白质乙酰化 作为一种重要的蛋白质翻译后修饰参与多种生理过程，因此在植物生长发育及环境适应中发挥着重要调控作用。蛋白质乙酰化修饰机制和生物学功能的解析可为作物育种及改良提供新的思路和方法。

How these many facets of acetylation and deacetylation are controlled and integrated, and how they influence the expression of specific genes as well as global changes in gene expression ...

近日，来自美国国立卫生研究院的Shiv I.S. Grewal在Molecular Cell上发表了论文Nucleosome remodeler exclusion by histone deacetylation enforces heterochromatic silencing and ...

Here, we reveal that when cells encounter nutrient stress, particularly a deficiency in amino acids, Sirtuin 2 (SIRT2) catalyzes the deacetylation of ACSS2 at the lysine residue K271. This results in ...

The accumulation of SIRT4 in the nuclei of kidney cells drives kidney fibrosis, so blocking the movement of this protein could be a potential therapeutic strategy against fibrosis.

HATs and HDACs respectively add and remove acetyl groups from lysine residues on the histone N-terminus. Histone acetylation and deacetylation allow interconversion between repressive and permissive ...

Every time you click a link to Wikipedia, Wiktionary or Wikiquote in your browser's search results, it will show the modern Wikiwand interface. Wikiwand extension is a five stars, simple, with minimum ...

Activation of macrophage TLR4 by bacterial endotoxins is important for the progression of sepsis, but the underlying ...

Study of python cardiac responses to feeding uncovers structural and epigenetic changes, enhancing understanding of heart ...

Tumors consist of cancer cells with different genetic, epigenetic, and phenotypic properties. Cancer stem cells are an important subpopulation of heterogeneous cancer cells and are capable of ...

In a study published in Cell Chemical Biology, a research team led by Prof. Tan Weihong and Prof. Wu Qin from the Hangzhou Institute of Medical of the Chinese Academy of Sciences has identified ...