In 1981, the first azole antifungal, the diazole ketoconazole, was introduced to the market; then, in the early 1990s the first-generation triazoles, fluconazole and itraconazole, became available.
北京大学药学院天然药物及仿生药物全国重点实验室刘涛团队在 Journal of the American Chemical Society 杂志发表了题为 Computational-Guided Discovery of Diazole Monosubstituted Tetrazines as Optimal Bioorthogonal Tools 的 ...
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