Mice express full-length protein ZBP1-L as well as an alternatively-spliced shorter isoform (ZBP1-S) containing only its two ...

Long-read sequencing uncovered hundreds of thousands of new isoforms not previously identified during development.

We all can acquire odd, wacky, or weird beliefs from online interaction. How does that happen? Gestalt psychology helps us ...

Investigators suggest that further research could help discover potential therapeutic approaches that leverage the alternative splicing-nonsense-mediated decay process.

RNA-sequencing has become a cornerstone in the study of gene expression, offering insights beyond mere mRNA transcript ...

Dr. Fuqua was the first to discover alternatively spliced transcriptional isoforms and somatic mutations in breast tumors. Recently mutations in ER have been rediscovered by a number of laboratories ...

Researchers at HSE University and the RAS Institute of Bioorganic Chemistry have discovered that a common method of studying ...

The authors present a valuable study exploring the interaction between JNK signaling and high sucrose feeding. The strength of evidence supporting these observations is solid, including multi-tissue ...

This manuscript describes the impact of modulating signaling by a key regulatory enzyme, Dual Leucine Zipper Kinase (DLK), on hippocampal neurons. The results are interesting and will be important for ...

CaMKII activates the HRI/eIF2α signaling pathway and inhibits the proteotoxicity induced by proteasome inhibition through ...