Understanding the precise mechanisms of monogenic autoinflammatory diseases provides crucial insights into the complex pathophysiology of more common multifactorial diseases, while treatments ...

Are inhibitors of the JAK/STAT Signaling Pathway a potential treatment for Parkinson Disease? How does -syn lead to activation of the JAK/STAT pathway, and how does this contribute to ...

Anzupgo is a topical pan-JAK inhibitor for the treatment of moderate to severe CHE. It inhibits the activation of JAK-STAT ...

New Mechanistic Insights Underscore Multiple Potential Roles for Elraglusib as an Immune Modulator in the treatment of ...

The team found a comparable protein in their test animals traveled to their muscles via the bloodstream and activated a ...

They send signals via what’s known as the JAK-STAT, a chemical pathway in your cells. By blocking parts of this pathway, JAK inhibitors prevent the inflammation caused by cytokines. Two JAK ...

Researchers investigate the anti-inflammatory and anti-prostate cancer properties of aged black garlic extract.

该积极意见标志着欧盟（EU）上市许可的最新进展，目前尚待欧盟委员会（EC）作出最终决定。如果获得批准，德戈替尼 (Delgocitinib)乳膏将成为首个专门针对中重度CHE成人患者（外用皮质类固醇治疗效果不佳或不适用）的外用药物。

The authors delve into the key signaling pathways that drive MM pathogenesis, including the PI3K/AKT/mTOR, RAS/MAPK, JAK/STAT ...

人民日报健康客户端记者搜寻国家药监局及药物临床试验登记与信息公示平台发现，截至9月16日，已有2款治疗重症斑秃的JAK抑制剂在我国获批上市，分别是礼来的巴瑞替尼和辉瑞的利特昔替尼。

9月2日，以“毒理智创未来，质效双轮驱动，领航新药发展”为主题的2024（第十二届）药物毒理学年会在上海隆重召开。有济医药参加了此次学术会议并受邀主题演讲和现场壁报展示，与参会专家学者、研究人员们进行了广泛交流。

New Mechanistic Insights Underscore Multiple Potential Roles for Elraglusib as an Immune Modulator in the <a target=_blank href=https ...