660) have overcome this obstacle by designing a peptide that mimics a TAC antigen. Vaccination of mice with the peptide mimotope reduced tumor growth and prolonged survival.

VAXINIA is under clinical development by Imugene and currently in Phase I for Hepatocellular Carcinoma. According to GlobalData, Phase I drugs for Hepatocellular Carcinoma have an 81% phase transition ...

Modulating enzyme activity by attaching a cofactor or a protein different from the enzyme has long been used in the construction of signaling molecules for the detection and/or dosage of small ...

OnCARlytics is under clinical development by Imugene and currently in Phase I for Bile Duct Cancer (Cholangiocarcinoma). According to GlobalData, Phase I drugs for Bile Duct Cancer (Cholangiocarcinoma ...

Sadam and colleagues used a next-generation phage display approach called mimotope variation analyses (MVA) to define epitope profiles predictive of MS progression in patients presenting with optic ...

Tetrodotoxin (TTX), which is found in various marine organisms, including pufferfish, shellfish, shrimp, crab, marine gastropods, and gobies, is an effective marine toxin and the cause of many seafood ...