Aristada is a prescription drug used for schizophrenia. Find out about possible interactions with alcohol, other drugs, ...

When cinacalcet is used, dose-modification of concomitantly administered drugs metabolized by CYP1A2, CYP2C9, CYP2C19 and CYP3A4 is not necessary. Cinacalcet does not pharmacokinetically interfere ...

As the furanocoumarins in grapefruit are broken down in the body, their resulting derivatives can block the action of CYP3A4. Thus, instead of being broken down as usual, more of the drug enters ...

Reported adverse drug events have increased from 30,000 to ... competitive inhibition of CYP2C19 Increased sedative effect [47] CYP3A4-mediated interactions Ketoconazole ↑ PPI effect Inhibition ...

Direct Oral Anticoagulants (DOACs) have significantly improved anticoagulation therapy – due to their ease of use, ...

FDA drug alerts in pulmonology, including drug approvals/warnings, vaccine approvals, medical device recalls/updates, and ...

观点一：阿奇霉素可明显干扰茶碱代谢，使茶碱血液浓度升高；两者不可联用。 茶碱在人体内通过肝药酶 CYP450 中的 CYP3A4、CYP1A2 进行代谢，而大环内酯类是 CYP3A4 及 CYP1A2 的抑制剂 [1] 。对于 CYP3A4 及 CYP1A2 酶活性较低的个体，茶碱的基础代谢比正常群体慢 ...

ROCKVILLE, Md. & EDMONTON, Alberta-- ( BUSINESS WIRE )--Aurinia Pharmaceuticals Inc. (NASDAQ: AUPH) (Aurinia or the Company) today announced that the Japanese Ministry of Health, Labour, and Welfare ...

Many of these drugs are metabolized by cytochrome P450 3A4 (CYP3A4), which has been estimated to be involved in the metabolism of ∼50% of prescription drugs and is therefore a common cause of ...

Biologics are drugs made from complex molecules manufactured using living microorganisms, plant, or animal cells. Many are produced using advanced biotechnology techniques. Biologics are sometimes ...

Could Taking Certain Drugs Reduce Risk of Ruptured Brain Aneurysm? June 5, 2024 — A new study suggests that people who take a few common drugs may have a decreased risk of having a bleeding ...

Drug or alcohol abusers ... pentazocine); may reduce effects and/or precipitate withdrawal symptoms. Potentiated by CYP3A4 inhibitors (eg, macrolides, azole antifungals, protease inhibitors).