Hot Spot. GWAS of tau PET scans found a single locus where SNPs (circles) were associated with higher tangle loads. The strongest signal came from SNP rs2113389 (gray diamond). [Courtesy of Nho et al.

Study demonstrates that glutathione (GSH) significantly reduces acetaldehyde levels, a key factor in hangovers, though ...

A study published in the peer reviewed journal Cannabis and Cannabinoid Research and available online through the U.S. National Library of Medicine explores the effects of Cannabistilbene I (a ...

Ratutrelvir was well-tolerated for 10 days and achieved consistent plasma levels in the predicted therapeutic window, without ...

Secondary efficacy analyses of the pivotal SEQUOIA-HCM trial continued to favor aficamten, supporting a potential role for ...

Did you know CBD is not for everyone? Cannabidiol (CBD) has gained significant popularity in recent years, touted for its potential therapeutic benefits and widely available in various forms, from ...

A team of international researchers has uncovered a new species of land flatworm in the United States, adding to the growing ...

A primary constraint for mitochondrial repression is access to cytosolic inorganic phosphate, which is determined by the glycolytic flux rate.

Repurposing of a drug designed for pain relief can quickly and reversibly slow biochemical and metabolic activities in cells and organs and could facilitate organ transplantation and prevent tissue ...

Direct Oral Anticoagulants (DOACs) have significantly improved anticoagulation therapy – due to their ease of use, ...

The drug is cleared by cytochrome P450 (CYP)3A4 metabolism. Peak plasma concentrations are achieved about 1.5 hours after oral administration. Its absorption is not affected by food. Eplerenone ...