Sage Therapeutics announced that Biogen has ended its partnership on the SAGE-324 program after the drug failed in a Phase II ...

In July, Biogen and Sage reported the failure of GABAA receptor positive allosteric modulator SAGE-324, also called BIIB124, ...

Rakkoo gabaa jimaa isaan mudate irratti qonnaan-bultoota Harargee komii isaanii BBCtti himan. Obbo Ahimad Muummee Imar Godina Harargee Bahaa Magaala Maayaatti qonnaan-bulaa yoo ta’an ...

Receptors between neurons are responsible for receiving these chemical messages, and a critical type of receptor is the ...

Studies suggest that the flavonoids (the chemicals found in plants) bind well to the GABAA neuroreceptors in the brain. I recommend getting chamomile in a tea. It is a lot cheaper than ...

Sage Therapeutics, Inc. (Sage) announced Thursday that Biogen Inc. (BIIB) has terminated its rights under the collaboration and ...

Fintel reports that on September 23, 2024, Oppenheimer upgraded their outlook for Marinus Pharmaceuticals (NasdaqGM:MRNS) ...

作为一种天然的异黄酮类化合物，葛根素在临床上被用于治疗心脑血管疾病。对小鼠DMV脑片的电生理试验结果显示，葛根素可显著降低动作电位频率。而在脑室内注射葛根素后，小鼠体重降低，原因在于肠道的脂肪吸收受到了抑制，脂肪排泄增加。这些结果表明葛根素可以抑制D ...

【导读】肿瘤微环境中的一些代谢物可以改变固有免疫功能。9月26日，武汉大学李友军教授研究团队在期刊《Advanced Science》上发表了研究论文，题为“Increases in 4-Acetaminobutyric Acid Generated ...

The company’s Phase 3 study design improvements, informed by earlier Phase 2 results, along with the drug’s mechanism of action which targets both synaptic and extrasynaptic GABAA receptors, suggest a ...

Warra kontirobaandii hojjetan miidha. Gatiin doolaaraa gabaa gurraachaa fi baankii yeroo wal fakkaatu garatti daldala kana gaggeessan hin qaban,'' jedhan. Dhimmoota ijoo ogeeyyiin dinagdee BBC'n ...

该研究表明，肠道对脂肪的吸收受到大脑直接调控，抑制这条“脑-肠轴”，会导致小肠上皮细胞的微绒毛缩短，从而缩小吸收表面积，减少对脂肪的吸收，增加脂肪通过粪便的排除，从而促进体重减轻。该研究还展示了来自中药葛根的天然化合物葛根素（puerarin）可以靶 ...