The beads are called nucleosomes. Each nucleosome is made of DNA wrapped around eight histone proteins that function like a spool and are called a histone octamer. Each histone octamer is composed ...

Diffuse midline glioma (DMG) is a highly aggressive and fatal pediatric high-grade glioma that primarily affects critical ...

How? Scientists are using ChIP and PCR to find out. To examine changes in histone modification during blood cell development in chickens, the investigators started with whole chromatin from ...

It is crucial for organisms to be able to control which genes are expressed in which cells and when. Naturally occurring chemical modifications of DNA-binding histone proteins are believed to play an ...

Breeding efforts have focused intensively on improving grain yield and quality in wheat (Triticum aestivum L.). Content and ...

Changing nutrient environments challenge cells as they affect both protein biosynthesis and cell cycle length. This work ...

The following is a summary of “Transient stabilization of human cardiovascular progenitor cells from human pluripotent stem cells in vitro reflects stage-specific heart development in vivo,” published ...

Epigenetics regulates gene expression through modifications, impacting health and disease. Aberrant patterns can lead to ...

It has only recently been discovered that single-celled organisms (bacteria and archaea) also have histones—proteins that ...

University of Cologne scientists identified histone H1.2 and PARP1 as potential therapeutic targets in ALS. Inhibiting these proteins reduced neurodegeneration in both human motor neurons and C.

Therapy candidate CS014 reversed remodeling of the pulmonary arteries in a preclinical model of pulmonary arterial ...

Diffuse midline glioma (DMG) is a highly aggressive and fatal pediatric high-grade glioma that primarily affects critical regions of the central nervous system, such as the pons, thalamus, and spinal ...