Whole-exome sequencing (WES) revealed a significant enrichment of rare variants in key IGF signaling components, particularly the IGF receptor 1 (IGF1R), in a cohort of Chinese Han individuals ...

KRIYA-586 is an investigational adeno-associated virus (AAV) gene therapy product engineered to express an antibody that inhibits Insulin-Like Growth Factor 1 Receptor (IGF1R), a key target implicated ...

The authors identified the IGF1-IGF1R ligand-receptor pair as a factor involved in the macrophage-mediated induction of memory-like Th17 cells, as confirmed by experiments using an IGF1R inhibitor.

Bio-Techne Corporation (NASDAQ: TECH) today announced it will showcase its portfolio of solutions advancing neuroscience ...

在癌症治疗的不断探索中，针对 Trop-2 的抗体药物偶联物（ADC）成为了新的研究焦点。近日，国际知名期刊 International Journal of Molecular Sciences 在线发表了一篇综述文章，由 Tomas Koltai ...

These actions collectively help protect neurons from damage. Specifically, flavones primarily counter epilepsy through interactions with pathways such as NF-κB p65, the TLR4/MyD88/NF-κB axis, PPAR-γ, ...