Tectonic的管理团队在最近的一次晚餐中强调，虽然伴有HFpEF的2组PH是TX45目前的目标，但仍有机会扩大该药物的应用范围。TX45作为更大产品管线的一部分显示出了前景。该候选药物在Ia期试验中已经显示出良好的安全性和药代动力学/药效学（PK/PD）特征。

在周一，Piper Sandler对Tectonic Therapeutics Inc. (NASDAQ:TECX)保持积极态度，重申"增持"评级，目标价为$76.00。该公司的乐观情绪与未来12个月的潜在催化剂有关，特别是其TX45治疗方案，这是一种针对2型PH HFpEF的relaxin激动剂——一种目前在美国影响约60万患者且尚无批准治疗方法的疾病。 Tectonic Therapeutic ...

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Tectonic Therapeutics Inc. (TECX) announced favorable Phase 1a topline data for its lead asset, TX45, a long-acting, potentially ...

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TX45 was well-tolerated with no observed immunogenicity, and demonstrated a favorable PK/PD relationship which was used to identify doses for the ...

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