Here, we reveal that when cells encounter nutrient stress, particularly a deficiency in amino acids, Sirtuin 2 (SIRT2) catalyzes the deacetylation of ACSS2 at the lysine residue K271. This results in ...
The message is interesting to a wider community working on kidney fibrosis, protein acetylation, and SIRT4 biology. (1) In the results part 3.9, an in vitro deacetylation assay employing recombinant ...