Sphingosine is a membrane component in all cells and constitutes 25% of the lipid in the myelin sheath. Sphingosine is phosphorylated by ubiquitously expressed sphingosine kinases. S1P regulates ...

In addition, women were even less likely to receive high-efficacy treatments such as natalizumab, anti-CD20 antibodies, or ...

Among 282 patients with pediatric-onset MS, 39% started high-efficacy therapy early (at ages 12-17), and 61% started late ...

A study has revealed significant therapeutic inertia in the treatment of women with multiple sclerosis (MS), highlighting ...

This is really important, because there have been case reports of patients experiencing relapses with natalizumab and fingolimod when they've discontinued the medication. That's why it's important for ...

A study has revealed significant therapeutic inertia in the treatment of women with multiple sclerosis (MS), highlighting gender disparities that could impact long-term health outcomes for women of ...

To address the unmet need for a cure for RTT, the therapeutic potential of adult Neural Precursor Cells (NPCs) was ...

The difference in DMT usage varied across different treatments and over time. Teriflunomide, fingolimod, and anti-CD20 therapies were significantly underused throughout their entire availability ...

A new study reveals how gender disparities cause therapeutic inertia in MS treatment for women, highlighting delays and ...

Looking back over the journey from our humble beginnings in 1999, exploring the impact NICE has had so far, and the changes we're making to ensure we continue to add value to an evolving health and ...

Diltiazem is used to treat high blood pressure (hypertension) and prevent chest pain (angina).