Trials evaluating the use of hypertonic saline solutions for resuscitation after traumatic injury have not shown an overall mortality benefit compared with isotonic fluid administration. The ...
Central pontine and extrapontine myelinolysis, regarded as the histopathological hallmark of hyponatraemia, has only occasionally been described in infants.21 Brain cell volume is affected by acute ...
hypernatraemia (s-Na >155 mmol/L), central pontine myelinolysis and seizures. The units hold the ability to abort the study if deemed necessary. The presence of SAR or SUSAR does not exclude the ...