Sepsis mortality, including a 28-day mortality, is associated with a genetic predisposition to gastroesophageal reflux disease.

MR pleiotropy and Cochran’s Q test were used to confirm the heterogeneity and pleiotropy of identified IVs, then four different models, including the inverse variance weighted model (IVW), MR-Egger, ...

The recent advances in high-throughput sequencing studies, integrated with findings derived from multimodal brain imaging data analyses and genome-wide association studies (GWAS) have expanded our ...

By Pooja Toshniwal Paharia Managing risk factors related to loneliness could still improve long-term health outcomes, ...

MR results can be biased by horizontal pleiotropy, but there are methods available to detect and allow for pleiotropy. We undertook a bidirectional MR analysis to test whether there is a causal ...

A large-scale genetic study involving over 1 million participants has uncovered more than 100 genes associated with anxiety.

Two additional indicators were also employed to detect directional horizontal pleiotropy and evaluate heterogeneity: the ...

The following is a summary of “Causal relationships between gut microbiome and aplastic anemia: a Mendelian randomization ...

A recent study led by researchers from the University of Edinburgh, UK and published in the journal Molecular Psychiatry ...

In a sensitivity analysis, none of the single-nucleotide polymorphisms were detected as heterogeneous and no significant pleiotropy was observed. "The analysis suggests that dietary intake of ...