The humanized monoclonal anti-VEGF antibody bevacizumab (Avastin ®, Genentech Inc., South San Francisco, CA) is a prototypic antiangiogenic compound, and has proven therapeutic benefit combined w ...

Danese et al., therefore, hypothesized that antiangiogenic treatment might be effective in animal models of IBD. They investigated the effect of ATN-161 on experimental colitis in mice.

The combination of ramucirumab with trifluridine/tipiracil failed to show improvements in overall survival vs TAS-102 alone ...

Merit Medical Systems, IncMMSI announced favorable 6-month results from the randomized arteriovenous (AV) fistula arm of its ...

In an international multicenter randomized phase 3 clinical trial led by Dana-Farber Cancer Institute, researchers tested the ...

Fairs has now been accepted into a medulloblastoma European multitarget metronomic antiangiogenic (MEMMAT) trial in Lille, ...

and colleagues conducted a phase 3 multicenter trial involving participants with advanced clear-cell renal cell carcinoma who had previously received immune checkpoint and antiangiogenic therapies.

Treatment with Cyramza plus Lonsurf did not improve overall survival compared with Lonsurf alone in heavily pretreated ...

In that case, there wouldn't really be any reason to change from where we are today, saving antiangiogenic agents for part of later-line therapy after progression on pembrolizumab-based treatment.

David A. Eichenbaum, MD, presented key data from two clinical trials focusing on therapies for age-related macular ...

Both TACE and TAE result in hypoxia, which stimulates angiogenesis, promoting tumor growth; thus combination of TACE with antiangiogenic agents may improve current results. To date, there is no ...