Secondary efficacy analyses of the pivotal SEQUOIA-HCM trial continued to favor aficamten, supporting a potential role for ...

Ratutrelvir was well-tolerated for 10 days and achieved consistent plasma levels in the predicted therapeutic window, without the need for ...

Possible interactions of omeprazole with other benzodiazepines that are metabolized by the cytochrome P450 system should ... effect of PPIs through CYP2C19. Inhibition of CYP2C19-dependent ...

Evidence suggests potential interactions between ART and some antipsychotic agents. Cytochrome P450 inhibitors have the potential to increase the concentration of clozaril and pimozide ...

Ratutrelvir was well-tolerated for 10 days and achieved consistent plasma levels in the predicted therapeutic window, without the need for co-administration of ritonavir Phase 2a study expected ...

Direct Oral Anticoagulants (DOACs) have significantly improved anticoagulation therapy – due to their ease of use, ...

存储条件：Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month. 生物活性：Ketoconazole (R-41400) 是一种咪唑类抗真菌剂，是一种 CYP3A4 和 CYP24A1 抑制剂。 IC50 和目标：CYP3A4、CYP24A1。 体外：酮康唑 (R-41400) ...

United Therapeutics Corporation (Nasdaq: UTHR), a public benefit corporation, today announced that five presentations and one poster across its commercial and development portfolio will be presented ...

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Many of these drugs are metabolized by cytochrome P450 3A4 (CYP3A4), which has been ... caused several cases of rhabdomyolysis 4, is an inhibitor of transporters such as P-glycoprotein, as well ...

Optinose (NASDAQ:OPTN), a pharmaceutical company focused on patients treated by ear, nose and throat (ENT) and allergy specialists, today announced the peer-review publication of a paper titled, ...

Learn what distinguishes common blood pressure medicines amlodipine and lisinopril, and how to know which one is best for you.