Repurposing of a drug designed for pain relief can quickly and reversibly slow biochemical and metabolic activities in cells and organs and could facilitate organ transplantation and prevent tissue ...
Massachusetts Institute of Technology has described proteolysis targeting chimeras (PROTACs) comprising an E3 ubiquitin ligase-binding agent coupled to cyclin-dependent kinase 9 (CDK9)-targeting ...
Researchers at Anadolu University and Bilecik Seyh Edebali University have described quinazolinone derivative compounds acting as EGFR (HER1; erbB1) inhibitors and apoptosis inducers reported to be ...
Being underground, they're potentially subjected to these forces from every direction. The most formidable stress inducers, though, would be earthquakes, of which hundreds occur each day. The ...
Phosplatin Therapeutics is a privately held, clinical stage pharmaceutical company developing best-in-class small molecule inducers of immunogenic cell death (ICD), a novel oncology immunotherapy ...
Most current autophagy inducers are chemical synthetics, so it is interesting to see how trehalose, as a natural substance, contributes to human well-being,” says Higashiyama. Trehalose’s role ...