The behavior of a person's genes doesn't just depend on the genes' DNA sequence - it's also affected by so-called epigenetic factors. Changes in these factors can play a critical role in disease.
The X and Y chromosomes, commonly referred to as the sex chromosomes, are one such pair. They determine the biological sex, reproductive organs, and sexual characteristics that develop in a person.
In the late 1980s, Linda Rose Frank began working with HIV-positive individuals at the University of Pittsburgh. At the time, those affected were mainly young men with a terrifying prognosis.
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