Manny Machado and the San Diego Padres square off against the Chicago White Sox and starter Chris Flexen on Saturday at 8:40 ...

ET, Jurickson Profar and the San Diego Padres (88-66) face Andrew Vaughn and the Chicago White Sox (36-118) at PETCO Park.

The San Diego Padres (88-66) take on the Chicago White Sox (36-118), who will be trying to halt a three-game losing streak, ...

What to look for from the top San Diego Padres and Chicago White Sox players and how to watch the game as they face off on ...

The Chicago White Sox (36-118) bring a three-game losing streak into a road contest against the San Diego Padres (88-66) at 8 ...

Lenyn Sosa hit a tying two-run homer with two outs in the ninth inning, but the Chicago White Sox lost their 118th game when ...

Oddsmakers have listed player props for Jurickson Profar, Andrew Vaughn and others when the San Diego Padres host the Chicago ...

Preview the Sept. 21 matchup between the San Diego Padres and Chicago White Sox with odds over/under, game spread, betting ...

Analyzing Friday’s Chicago White Sox at San Diego Padres odds and lines, with MLB expert picks, predictions and best bets.

Preview the Sept. 21 matchup between the San Diego Padres and Chicago White Sox with recent trends, how to watch, livestream ...

The San Diego Padres (87-66), led by Jurickson Profar, host Andrew Vaughn and the Chicago White Sox (36-117) at 9:40 PM ET on ...

The Chicago White Sox are closing in on matching the 1962 New York Mets for the most losses in modern-day Major League ...