The role of this isoform has been elusive so far and this first demonstration represents a substantial advance in our understanding of the complex role(s) of p53 isoforms. The revised article ...
Understanding protein function within living cells is crucial for basic research and therapeutic development. Protein kinetics in living cells provide more relevant insights compared to studies in ...
However, in the presence of the auxiliary subunit TARP γ-2, ABHD6 accelerated the deactivation and desensitization of either GluA1 and GluA2(Q) containing homomeric receptors independent of their ...
Investigators suggest that further research could help discover potential therapeutic approaches that leverage the alternative splicing-nonsense-mediated decay process.